南农姜平教授研究团队发现一

　　1、NADC30毒株与中国的高致病性毒株重组。

　　2、新重组毒株有类似高致病性的毒力。

　　3、TJM-F92、 R98疫苗能提供对重组毒株的保护。

　　原文：

　　1、The FJ1402 strain was a recombinant of NADC30 and the Chinese HP-PRRSV strain.

　　2、FJ1402 had a similar pathogenicity with HP-PRRSV strain BB0907.

　　3、TJM-F92 and R98 could partly provide protection against FJ1402 challenge.

　　来源：

　　Pathogenicity and antigenicity of anovel NADC30-like strain of porcine reproductive and respiratory syndrome virus emerged in China. Veterinary Microbiology Volume 197, 25 December 2016, Pages 93-101.

　　南农姜平教授研究团队发现二

　　1、这些结果表明 PRRSV 当前疫苗免疫压力和净化下，会出现更多的重组毒株及压力。

　　2、25%的重组毒株中都能发现有JXA1-R的基因特征，与之相关。

　　原文：

　　1、Recombination analyses showed that nine of 28 isolates and one isolate from other laboratory were potential complicated recombinants between the vaccine JXA1-R-like strains and predominant circulating strains.

　　2、These results indicated an increase in recombination rates of PRRSV under current vaccination pressure and a more pressing situation for PRRSV eradication and control in China.

　　来源：

　　Emergence of mosaic recombinant strains potentially associated with vaccine JXA1-R and predominant circulating strains of porcine reproductive and respiratory syndrome virus in different provinces of China.Zhao et al. Virology Journal (2017) 14:67.

　　中农杨汉春教授研究团队发现一

　　1、新重组毒株TJnh1501被发现。

　　2、新发现的毒株基因特征是NADC30毒株与高致病性减毒活疫苗（江西毒株）的杂交的。

　　3、重组毒株显示出中等毒力对仔猪发病。

　　原文：

　　1、The genomic characterization of a type 2 PRRSV (TJnh1501) was analyzed.

　　2、The isolate TJnh1501 was shown to the recombinant virus between NADC30-like and MLV-like.

　　3、The isolate TJnh1501 shared intermediate virulence for piglets.

　　来源：

　　A recombinant type 2 porcine reproductive and respiratory syndrome virus between NADC30-like and a MLV-like:Genetic characterization and pathogenicity for piglets. Infection, Genetics and Evolution Available online 13 July 2017.

　　中农杨汉春教授研究团队发现二

　　1、CHsx1401的NADC30毒株是中毒毒力毒株。

　　2、减毒活疫苗不能降低临床感染和肺部损失。

　　3、减毒活疫苗部分降低病毒血症。

　　4、减毒活苗提供有限的交叉保护对NADC30毒株。

　　原文：

　　1、The PRRSV NADC30-like CHsx1401 was shown to be a moderate virulent virus for piglets.

　　2、MLV vaccines could not reduce the clinical signs and lung lesions of the pigs challenged.

　　3、MLV vaccines were partially efficacious in the reduction of viral loads.

　　4、MLV vaccines are shown to provide extremely limited cross-protection against PRRSV NADC30-like.

　　来源：

　　Efficacy evaluation of three modified-live virus vaccines against a strain of porcine reproductive and respiratory syndrome virus NADC30-like.Veterinary Microbiology Volume 207, August 2017, Pages 108-116.

　　小结

　　1、目前NADC30毒株与JXA1高致病性毒株、JXA1-R疫苗毒株重组成新毒株的案例非常多，成为中毒毒力或高致病性毒力的新毒株。

　　2、目前JXA1-R疫苗对这种新毒株提供有限的保护，TJM-F92、 R98疫苗能够对重组毒株提供保护。

　　瑞兰安

　　高致病性蓝耳病基因缺失弱毒活疫苗